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Cytological studies on conjunctival epithelium of epidemic Keratoconjunctivitis:Comparative studies of cellular lesions in human conjunctival epithelium infected with adenovirus type 8 in tissue culture Seiji SUGIURA 1 , Yuzo SEGAWA 1 , Yukifumi NAKAIZUMI 1 , Doichi OTA 1 , Kaichi WAKUI 1 , Nobuo KUSANO 2 1Department of Ophthalmology, the Branch Hospital of the University of Tokyo 2The Department of Pathology, The Institute for Infectious Diseases, The University of Tokyo pp.304-309
Published Date 1959/2/15
DOI https://doi.org/10.11477/mf.1410206569
  • Abstract
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In order to study the changes of the conjunctival epitheliar cells in epidemic keratocon-junctivitis, adenovirus type 8 was inoculated into the tissue culture. The cellular changes appeared in the tissue culture coincided with those of .the conjunctival epithelial cells of epi-demic keratoconjunctivitis.

The changes which occurred mainly in the nucleus were classified in Stage 1, 2, 3 and 4, the Stage 3 and 4 being further divided into Type A, B, and C.

The early change was the formation of vacuoles in the nucleus.


Copyright © 1959, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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