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緒言
思春期に発症し,その後緩徐な経過を辿りつつ次第に視力低下をきたし,絶えず失明の危機にさらされているStargardt型黄斑部変性症に対しては,現在のところ他の遺伝性網膜変性症とともに的確な治療法がない。
1966年Braley1)は,3例の黄斑部変性症に光凝固術を行ない,2例に好結果を得,慎重に試みるならば変性病巣の進展を阻止し,かつ視力改善をもたらし希望のもてる療法の一つとなるであろうと述べている。
A 22-year-old woman first noted visual dis-turbance at 10 years of age. There was only a slight yellow area temporal to the optic disc and no other sign in the fundus. Vision was 0.3 in either eye. She was treated with steroid and vitamin for 4 months and improved with a vision of 0.5. Nine years later she stated that vision became blurred suddenly, 0.02 in the right and 0.2 in the left. The fundus showed typical Stargardt's macular degeneration : the macula revealed a slate-gray, slightly elevated lesion with few small pigmentation.
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