Efficacy of switching from concomitant therapy to fixed combination in glaucoma patients Ai Yamada 1 , Satoshi Sugaya 1 , Shinsuke Hori 1 , Jun Sasaki 1 , Kazuhiro Kosaku 1 , Yoshio Yamazaki 1 1Dept of Ophthalmol,Nerima Hikarigaoka Hosp,Nihon Univ Sch of Med pp.1035-1038
Published Date 2012/7/15
DOI https://doi.org/10.11477/mf.1410104284
  • Abstract
  • Look Inside
  • Reference

Abstract. Purpose:To assess the efficacy of switching from concomitant therapy to fixed combination. Method:Thirty-five patients with ocular hypertension and glaucoma were enrolled into the study. We investigated the adherence of topical medication and intraocular pressure(IOP)in patients before and after switching. Results:After switching to fixed combination,patients with poor adherence decreased from 20 cases to 12 cases. In patients with fair adherence before switching,mean IOP was significantly higher after switching compared to that before switching(p=0.019). In patients with poor adherence before switching,there was no significant difference. Conclusion:These results show that fixed combination might be useful in patients with poor adherence.

Copyright © 2012, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院