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The Ordinary Type of Malignant Fibrous Histiocytoma Presenting with Constitutional Symptoms Such as Pyrexia, Deep Anemia and Liver Dysfunction. Case Report Takeshi Ishii 1 , Shin-ichiro Tatezaki 1 , Tsukasa Yonemoto 1 , Shintaro Iwata 1 , Yoshio Takeuchi 1 1Division of Orthopaedic Surgery, Chiba Cancer Center Hospital Keyword: malignant fibrous histiocytoma , 悪性線維性組織球腫 , cytokine , サイトカイン , G-CSF , 顆粒球コロニー刺激因子 pp.1065-1069
Published Date 2005/9/1
DOI https://doi.org/10.11477/mf.1408100188
  • Abstract
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 We reported a case of malignant fibrous histiocytoma (MFH) presenting with constitutional symptom such as pyrexia. A 29-years-old man with a large tumor of his right thigh was referred to our hospital after a close inspection by his internist for high fever, leukocytosis and severe anemia. The tumor was diagnosed as a sarcoma by needle biopsy. Hip disarticulation was performed. The excised tumor was diagnosed as the ordinary type of MFH. After the surgery the patient's symptos promptly improved within two weeks. The serum level of G-CSF and IL-6 were very high before surgery and normalized after surgery. The tumor was believed to have been responsible for the production of these cytokines. The patient has survived disease free for eight years after surgery.


Copyright © 2005, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1286 印刷版ISSN 0557-0433 医学書院

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