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PATHOLOGICAL STUDY OF WILLIS'S CIRCLE IN AUTOPSY CASES OF POLYCYSTIC KIDNEY DISEASE Hidetoshi Ikeda 1 , Takashi Yoshimoto 1 1Division of Neurosurgery, Institute of Brain Diseases, Tohoku University School of Medicine pp.909-913
Published Date 1987/10/1
DOI https://doi.org/10.11477/mf.1406205980
  • Abstract
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Two autopsy cases of polycystic kidney disease with intracranial aneurysms were reported. We made a pathological study of their vascular system with special reference to Willis's circle in order to prove the inherent abnormality of vascular system in patients with polycystic kidney disease.

A 57-year-old man was revealed to have poly-cystic kidney disease with left middle cerebral artery aneurysm and aortic stenosis. The other 58-year-old man was revealed to have polycystic kidney disease with cerebral aneurysms both in anterior communicating artery and basilar artery, aortic dissecting aneurysm, cerebral infarction and myocardial infarction.

Histologically, both abrupt interruption and par-tial disappearance of internal elastic lamina are found frequently in the wall of Willis's circle. This abnormality of internal elastic lamina may be attributable to congenital factors and rise the frequency of occurrence of intracranial aneurysms in polycystic kidney disease.


Copyright © 1987, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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