雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

EFFECTS OF PHENOBARBITAL ON EEG AND SENSORY EVOKED POTENTIALS IN NORMAL CAT BRAIN Mikio Takaya 1 , Kouzo Moritake 1 , Tsuneki Konishi 1 , Hideyuki Suwa 1 , Hajime Handa 1 , Tomio Koshikawa 2 , Katsuhiko Okumura 2 , Ryohei Hori 2 1Department of Neurosurgery Kyoto University Hospital 2Department of Pharmacy, Kyoto University Hospital pp.785-790
Published Date 1985/8/1
DOI https://doi.org/10.11477/mf.1406205563
  • Abstract
  • Look Inside

In adult cats, authors studied changes in para-meters obtained by the recordings of sensory evoked potentials following cumulative intrave-nous administration of phenobarbital. P1 and N1 of cortical SEP showed gradual tendencies to de-crease in amplitude and to increase in latency with increasing barbiturate dose. These changes preceded to the appearance of burst-suppression activity on electroencephalogram. At this point I-II and III-IV interpeak latencies of BAEP showed statistically significant increase. BAEP and all early components of SEP ( I・II・MI) persisted in the extremely high serum concentration of phenobarbital. Furthermore, II-III interpeak la-tency of BAEP showed no statistically significant increase.

These experimental results suggest that sensory evoked potentials will provide useful information in the assessment of the brainstem function in patients under deep coma.


Copyright © 1985, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

関連文献

もっと見る

文献を共有