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CEREBRAL MIXED TUMOR:GLIOBLASTOMA:FIBROSARCOMA WITH METAPLASTIC BONE FORMATION Osamu Nakamura 1 , Hiroaki Yamamoto 1 , Akira Teramoto 1 , Kintomo Takakura 1 , Kazuo Nagashima 2 1Department of Neurosurgery University of Tokyo 2Department of Pathology University of Tokyo pp.1185-1190
Published Date 1983/12/1
DOI https://doi.org/10.11477/mf.1406205230
  • Abstract
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The authors report a case in which left deep temporal fibrosarcoma with calcified area develop-ed about 6 months after radiation therapy for left temporal astrocytoma.

A 37 year-old woman was admitted to our clinic because of headache and visual deterioration. CT scan and angiography suggested left deep temporal glioma and on August 5, 1980, partial resection was performed. Histological sections showed ast-rocytoma G 2. Postoperative course was uneventful and she left the hospital after radiation therapy of 50 Gy. On March, 1981, right hemiparesis wasnoticed and progressed rapidly. CT scan suggested left temporal tumor recurred. On March 30, 1981, second operation was performed and this time, histological sections showed glioblastoma. After operation, β-Interferon (IFN) was given intra-tumorally via Ommaya's reservoir (3×106 IU, daily). But in spite of IFN therapy, tumor became larger and she died on June 30, 1981.

Autopsy revealed coexistence of glioblastoma and fibrosarcoma with metaplastic bone formation. A brief discussion concerning the problem of cerebral mixed tumors follows the description of the case.


Copyright © 1983, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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