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【抄録】 異なった施設間での事象関連電位(ERP)データの比較可能性を検討するため,測定方法を日本脳波筋電図学会の標準的測定法を基にできるだけ統一して,同一被検者のERPを5つの施設で測定し,P 300成分の一致度を検討した。対象は健常成人男性5例で,ERP課題にはoddbal1課題(鍵押し課題)を用いた。その結果,同一被検者におけるP 300成分の出現の有無については,視察的にいずれの施設でも一致した結果が得られた。さらにP 300頂点潜時と振幅値のバラツキおよび施設間の一致度を,分散分析とその結果を基に計算した級内相関係数を用いて検討した。その結果,潜時・振幅ともに施設間のバラツキは被検者間のバラツキよりも小さく,級内相関係数でみても比較的良好な施設間の一致度が得られた。今後より高い一致度を得るために必要な条件についても検討を行った。
To examine reliability of ERP data across facilities, we recorded ERPs of 5 paid healthy male volunteers at 5 collaborative research facilities, with each subject visiting all facilities for measurements. ERPs were recorded according to the designated conditions of Japan Society of EEG and EMG, employing the oddball paradigm for the ERP-eliciting task. Visual analyses demonstrated that ERP waveforms, particularly the P300 component, for each subject recorded at five different facilities were almost similar with each other. Furthermore, intraclass correlation analyses were conducted in order to examine reliability for the P300-peak amplitude and latency data across different facilities. As a result, good correlation coefficients were obtained for both measures, with the variances across facilities being much less than those for subjects. Based upon these results, several suggestions were made to enhance reliability for P300 measures across different facilities.
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