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Wandering Behavior in Schizophrenia Successfully Treated by Combined Therapy Using Olanzapine and Paroxetine:A case report Yuko FUKUNAKA 1 , Hiroko HORI 1 , Jun NAKAMURA 1 1Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Japan Keyword: Schizophrenia , Obsessive-compulsive symptoms , Wandering behavior , Paroxetine , Olanzapine pp.1013-1018
Published Date 2007/10/15
DOI https://doi.org/10.11477/mf.1405101080
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 We encountered a case of schizophrenia with wandering behavior that showed marked improvement due to combined therapy using olanzapine and paroxetine. Although negative and positive symptoms were improved by olanzapine monotherapy, wandering behavior remained. As the patient's wandering behavior was considered to be an obsessive-compulsive symptom, we added paroxetine. One week later his wandering behavior reduced both subjectively and objectively. On his discharge from hospital, his wandering behavior showed complete remission(Y-BOX score 22→0). It is not rare that schizophrenic patients also experience obsessive-compulsive symptoms, and recent literature shows that combined therapy using SSRIs and atypical antipsychotics are useful in such cases. To our knowledge, this is the first case report that focuses on wandering behavior in schizophrenia and its treatment.


Copyright © 2007, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-126X 印刷版ISSN 0488-1281 医学書院

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