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Brain Natriuretic Peptide as a Biochemical Marker of Perioperative Potential Ventricular Dysfunction in Cardiac Surgery Patients with Cardiopulmonary Bypass Hiroshi Furukawa 1 , Mitsuhiro Hachida 1 , Hiroyuki Watanabe 1 , Fuminaga Suetsugu 1 , Hiroyuki Muranaka 1 , Naohiro Nose 1 , Tetsuya So 1 , Teruo Iwata 1 , Hitoshi Nishikawa 1 , Kosei Yasumoto 1 1Department of Surgery II. School of Medicine, University of Occupational and Environmental Health, Japan Keyword: 脳性ナトリウム利尿ペプタイド(BNP) , 開心術 , 術後心不全 , brain natriuretic peptide(BNP) , cardiac surgery , postoperative heart failure pp.395-399
Published Date 2001/4/15
DOI https://doi.org/10.11477/mf.1404902277
  • Abstract
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 We evaluated the change of brain natriuretic peptide(BNP) in patients undergoing cardiac surgery withcardiopulmonary bypass (CPB), and compared it withpatients undergoing non-cardiac surgery. The subjectswere 17 consecutive patients undergoing cardiac surgerywith CPB and 7 non-cardiac surgery patients undergoing graft replacement for infrarenal abdominal aorticaneurysm (AAA) from August, 1999 to March, 2000.The perioperative level of BNP was measured on thepreoperative day and 1 day, 3 days, 5 days and 1 weekafter the operation. The level of BNP remained highuntil one week after cardiac surgery with CPB, butslowly decreased to the normal range by one week afternon-cardiac surgery. From these results, BNP might bea good indicator for potential ventricular dysfunctionand damage due to cardiac surgery with CPB.


Copyright © 2001, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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