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A case of aortitis syndrome which presented coarctation of aorta due to intraluminal flap formation in the middle of the thoracic aorta Ai Nakaji 1 , Michiko Ikezawa 1 , Mitsuko Kondo 1 , Masahiko Kawakami 1 , Kimio Konno 1 , Yoshio Takizawa 1 , Yoshiro Uetsuka 2 , Naohide Tanaka 2 , Hitoshi Koyanagi 3 1Department of Internal Medicine 1, Tokyo Women's Medical College 2Department of Cardiology, Tokyo Women's Medical College 3Department of Cardiosurgery, Tokyo Women's Medical College pp.209-213
Published Date 1989/2/15
DOI https://doi.org/10.11477/mf.1404205428
  • Abstract
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We present a rare case of aortitis syndrome asso-ciated with dilatation of aorta and coarctation-like effect due to the intraluminal flap formation originated from dissected wall of the aorta.

A 31-year-old woman was admitted to our hospitalcomplaining of shortness of breath, palpitation and cough. On admission, her physical status showed con-gestive heart failure and hypertension of upper extre-mities and hypotension of lower extremities. Bruits were audible over the neck, the anterior chest and the back. Serological studies showed active inflamma-tion. Chest X-ray film showed upper mediastinal widening, cardiomegaly and pulmonary edema. Aortitis syndrome was strongly suggested by these clinical findings, so that prednisolone therapy was started on 3rd hospital day. Special examinations were performed several days later when inflammato-ry changes showed a tendency to improve.

Chest CT scan, RI angiography and MRI studies showed an aneurysmal dilatation from the ascending aorta to the mid-thoracic aorta. Aortography demo-nstrated a flap at the terminal portion of this aneury-smal dilatation and grade II (Sellars) aortic regurgi-tation. There was a pressure difference of 80 mmHg between the parts abutting cranial and caudal sides of the flap.

A surgical operation was, then, performed to cor-rect the pressure difference. The disscted wall was extruded toward the aortic lumen creating a flap (2 cm in length). This flap was resected and an arti-ficial graft was inserted. Histologically, the flap con-sisted of adventitia, media and intima. The adven-titia and media were accompaniied by infiltration of inflammatory cells and the elastic fibers of the media were torn diffusely showing that the dissection was due to mesoaortitis.

Catheterization and aortography were performed after the operation which confirmed that it had been made successfully.


Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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