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極端な肥満を伴った肺胞低換気症候群はPickwickian Syndromeとよばれるが,本邦では,一之沢ら1),沼野ら2),西田ら3)による症例報告があるのみである。著者らは最近,中等度の肥満を伴った肺胞低換気症候群で,経過観察中広汎な心筋梗塞を発生し,冠動脈造影上ほぼ正常所見を示した症例を経験し,病態生理学上きわめて興味深い症例と思われるので報告する。
A case of 42 year-old male with obesity, alveolar hypoventilation syndrome, erythrocytosis, pulmonary hypertension, right ventricular hyper-trophy and right ventricular failure, suggesting Pickwickian syndrome, is reported. On the course of followup, the patient had an attack of extensive anterior and high lateral wall myo-cardial infarction with good recovery. Coronary angiogram 11 months after the infarction showed 30% stenosis of anterior descending artery, and other coronary arteries and branches were within normal limits. Pathophysiology of the case is discussed.
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