血圧と脈波伝達速度との関連について

Study on Relationship between Blood Pressure and Pulse Wave Velocity.

　動脈硬化に関しては従来幾多の研究報告があるにも拘らず，その硬化度の数量的表現については未だ適当な方法が無い。我々が通常行つている触診法は検者各個人の主観を伴い，且又被験者の皮膚及び皮下組織等の影響もあつて，該法により動脈硬化度を数量的に表現することは極めて困難である。

　我々は動脈硬化の程度を数量的に表現しようとして多年努力して来たが，その一つの試みとして，波動が物体を伝わる時，物体の硬度が高い程その伝達速度が大であるという物理学的事実を利用し，脈波伝達速度を測定して逆に血管壁の伸展性を表現しようとした。又この脈波伝達速度と血圧及び年齢との関係についても観察を行つた。得た結果は以下の通りである。

The relationship between the length of arm and the lenght of radial artery was determined in thirty-two corpses and an equation was gained. The length of arm was measured in the living bodies, then the length of the vessel was calculated by this equation.

On the other hand, the electrocardiogram and the radial pulse wave were simultaneously recorded, and the transmission time of pulse wave between the beginning of R wave of electrocardiogram and the initial deflection of pulse wave was measured (Fig 1). The velocity of pulse wave was calculated from these two values mentioned above.

385 adults examined in this study were divided into two groups : one was hypertensive group and the other was normal subjects.

As a rule, the velocity of pulse wave was greater in the hypertensive patients than in the normal persons. In the relation of the systolic or diastolic blood pressure to the velocity of pulse wave, the higher the blood pressure, the greater was the velocity of pulse wave.

The expansibility of the arterial wall was calculated by Hill's equation⁷⁾. Then it was concluded that the expansibility of the arterial wall in hypertensive group and older persons was smaller than in younger and normal subjects.