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Esophageal MALT Lymphoma:Focusing on Key Points of Diagnosis Tsuneo Oyama 1 , Akiko Takahashi 1 , Satoshi Shiozawa 2 1Department of Endoscopy, Saku Central Hospital Advanced Care Center, Saku, Japan 2Department of Pathology, Saku Central Hospital Advanced Care Center, Saku, Japan Keyword: 食道 , 食道悪性リンパ腫 , 食道MALTリンパ腫 , 食道ESD pp.884-892
Published Date 2023/7/25
DOI https://doi.org/10.11477/mf.1403203271
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 Esophageal MALT(mucoid-associated lymphoid tissue)lymphoma is a rare disease. Since its main locus is the submucosa, it shows submucosal tumor-like morphology. It is a soft submucosal tumor with a positive cushion sign because of the several associated cellular components. When it infiltrates into the epithelium, it destroys the proliferative zone and forms an indistinct depression. Histologically, it is characterized by a lymph follicle-like structure. Therefore, the EUS(endoscopic ultrasound)indicates a lymph follicle-like hypoechoic mass in the submucosal layer. Additionally, when MALT lymphoma progresses in the longitudinal direction, it acquires a giant tree-like shape and appears like a stenosis on an endoscope ; nonetheless, it being a soft tumor, only a few subjective symptoms are presented. Differential diagnoses include leiomyoma and granular cell tumor ; however, MALT lymphoma can be differentiated based on its softness and lymph follicle-like structure observed on EUS. A biopsy of the submucosa is required for a definitive diagnosis.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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