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Diagnosis and Eradication Therapy of NHPH Mototsugu Kato 1 , Momoko Tsuda 1 , Mitsuru Kawarazaki 1 , Ryoko Ebara 1 , Kimitoshi Kubo 2 , Katsuhiro Mabe 3 1Hokkaido Cancer Society, Sapporo, Japan 2Department of Gastroenterology, National Hospital Organization, Hakodate National Hospital, Hakodate, Japan 3Junpukai Health Maintenance Center Kurashiki, Kurashiki, Japan Keyword: 感染診断 , H. suis , H. heilmannii , H. pylori , PCR法 pp.37-42
Published Date 2023/1/25
DOI https://doi.org/10.11477/mf.1403203089
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 There is now just one approach that can be used in routine clinical practice to diagnose NHPH(Non-Helicobacter pylori Helicobacter)infection, and that is pathological examination. Helicobacter suis was successfully cultured from human gastric biopsy tissue recently. High-sensitivity and specificity polymerase chain reaction tests and antibody tests have also been developed at the research level. However, urease activity-based tests are not appropriate for NHPH diagnosis. In the future, as the significance of NHPH gastritis becomes more widely understood, we anticipate that the NHPH diagnostic method will be given for manufacturing and insurance approval. One-week triple therapy with PPI/P-CAB plus amoxicillin, clarithromycin, or metronidazole is successful for treating NHPH infection and is similar to the treatment for Helicobacter pylori infection. It is crucial to spread diagnostic techniques for NHPH infection to clarify the pathogenesis of the condition.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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