Stomach and Intestine(Tokyo) Volume 52, Issue 8 (July 2017)
Japanese

Immunohistochemical Staining of Gastrointestinal Mesenchymal Tumors other than Lymphoproliferative Disorders Seiichi Hirota 1 1Department of Surgical Pathology, Hyogo College of Medicine, Nishinomiya, Japan Keyword: gastrointestinal mesenchymal tumor , GIST(gastrointestinal stromal tumor) , spindle type , epithelioid type pp.1019-1029
Published Date 2017/7/25
DOI https://doi.org/10.11477/mf.1403201125
  • Abstract
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 GISTs(gastrointestinal stromal tumors)are the most common mesenchymal tumors of the gastrointestinal tract. As very effective drugs targeting specific molecular targets can be used for the treatment of GIST, it is very important to accurately diagnose the mesenchymal tumors of the gastrointestinal tract. Because various types of soft tissue tumors may arise in the gastrointestinal wall, a precise differential diagnosis between GISTs and the other types of tumors needs to be done. Although most GISTs strongly express KIT, some PDGFRA-mutant epithelioid GISTs might not show immunohistochemically detectable KIT expression. For accurate differential diagnosis of various gastrointestinal mesenchymal tumors, knowledge of specific immunohistochemical staining pattern for each tumor type is required.


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基本情報

05362180.52.8.jpg
胃と腸
52巻8号 (2017年7月)
電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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