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要旨●pT1大腸癌363病変(陥凹型癌144病変,隆起型癌219病変)を対象として,肉眼所見とSM浸潤距離との関連を検討した.陥凹型pT1大腸癌において,SM浸潤距離と相関し,粘膜下層深部浸潤を示唆する有意な肉眼所見は,腫瘍径1cm以上,緊満感,2型進行癌類似形態,ひきつれ,台状挙上,粘膜下腫瘍様立ち上がり,深い陥凹,無構造化,強い発赤,平滑な陥凹縁,であった.一方,陥凹縁の不整はSM浸潤距離と有意な逆相関がみられ,浅い粘膜下層浸潤を示唆する有意な肉眼所見であった.隆起型pT1大腸癌において,SM浸潤距離と相関し,粘膜下層深部浸潤を示唆する有意な肉眼所見は,緊満感,ひきつれ,無構造化,白苔付着,強い発赤,であった.
We examined the relationship between macroscopic findings and submucosal(SM)invasion depth in 363 pT1 colorectal cancer lesions(depressed type, 144 lesions; protruded type, 311 lesions). In cases of depressed-type pT1 colorectal cancers, significant macroscopic findings, suggestive of invasion of the SM layer, that were correlated with SM invasion depth were as follows: a tumor diameter of 1 cm or larger, a feeling of tension, appearance resembling type 2 cancer, tightening, table-like protrusions from the lesion, protrusion of SM tumor, deep depression, non-structure, strong reddening, and smooth depressed borders. On the other hand, a significant inverse correlation between irregular borders and SM invasion depth was observed, and significant macroscopic findings were suggestive of invasion of the shallow SM layer. In cases of protruded-type pT1 colorectal cancers, significant macroscopic findings, suggestive of invasion of the SM layer, that were correlated with SM invasion depth were as follows: a feeling of tension, tightening, non-structure, white coating, and strong reddening.
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