Pathological Characteristics of the Role of Radiological Diagnosis of the Depth of Invasion in Early Gastric Cancer Yasuharu Kaizaki 1 , Tamon Miyanaga 2 , Kenji Dohden 2 , Masakazu Hattori 2 , Yasuo Hashizume 2 , Hiroyuki Aoyagi 3 , Naoyuki Ibe 3 , Toshie Hara 1 , Kouji Urasaki 1 1Department of Pathology, Fukui Prefectural Hospital, Fukui, Japan 2Department of Surgery, Fukui Prefectural Hospital, Fukui, Japan 3Department of Gastroenterology, Fukui Prefectural Hospital, Fukui, Japan Keyword: 早期胃癌 , 病理 , 切除標本 , 深達度診断 pp.583-591
Published Date 2015/5/24
DOI https://doi.org/10.11477/mf.1403200285
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 We examined the accuracy of macroscopic findings for the diagnosis of the depth of invasion in early gastric cancer using photographs of resected specimens obtained from endoscopic submucosal dissection or surgery. In any macroscopic type, findings suggesting submucosal invasion alone showed high specificity but low sensitivity. However, when the findings were combined, increased sensitivity was observed and specificity remained high. Highly specific findings that indicated deep submucosal invasion were “depression on top of the protrusion,”in a protruded lesion; and“table-like elevation,” in a depressed lesion without ulceration. In a depressed lesion with ulceration, findings of“table-like elevation,”“non-structure in the depression,”and“fusion of folds”particularly showed high specificity. Regardless of the presence or absence of these findings, there was no significant difference in depth submucosal invasion of the tumor. For a diagnosis of the depth of invasion in early gastric cancer, it may be necessary to understand the features and limitations of macroscopic findings.

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