胃癌の深達度診断における病理のevidence

Pathological Evidence for the Diagnosis of Depth of Invasion of Gastric Cancer

要旨●胃癌の深達度に関わるevidenceを紹介した．胃癌の深達度はリンパ節転移や腹膜播種の予測因子として最も重要な因子である．深達度とリンパ節転移率は正の相関を示すが，特に粘膜下層の浸潤距離はリンパ節転移率に関連性がある．漿膜への腫瘍浸潤は腹膜播種との関連性が深い．深達度は胃癌の予後に直結しているが，現在の深達度判定法は，厳密性がやや不足している．今後は，予後予測因子として正確で再現性の高い深達度判定の確立が必要である．

　We introduced evidence related to the depth of invasion in gastric cancer. The depth of invasion is a critical factor in predicting both lymph node metastasis and peritoneal dissemination. A positive correlation exists between invasion depth and lymph node metastasis rates, with the extent of submucosal invasion playing a key role. Tumor invasion into the serosa is strongly associated with peritoneal dissemination. Since the depth of invasion is directly linked to gastric cancer prognosis, precise diagnostic methods are essential. Future efforts should focus on establishing more reliable and reproducible methods to improve prognostic evaluation.