Japanese

Prospective Study of the Usefulness of Type B2 Vessel Determined by the Japan Esophageal Society Classification of Magnified Endoscopy for the Diagnosis of Superficial Esophageal Squamous Cell Carcinoma Manabu Takeuchi 1 , Satoru Hashimoto 2 , Masaaki Kobayashi 2 , Gen Watanabe 3 , Ken-ichi Mizuno 2 , Yuichi Sato 1 , Yoichi Ajioka 3 , Yutaka Aoyagi 1 1Department of Gastroenterology, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan 2Department of Endoscopy, Niigata University Medical and Dental Hospital, Niigata, Japan 3Division of Molecular and Diagnostic Pathology, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan Keyword: 食道表在癌 , 深達度 , 拡大内視鏡 , B2血管 , 日本食道学会分類 pp.164-172
Published Date 2014/2/25
DOI https://doi.org/10.11477/mf.1403114069
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 The accuracy of the diagnosis of invasion depth in superficial esophageal SCC(squamous cell carcinoma)was evaluated by Type B2 microvessel in a new classification established by JES(the Japan Esophageal Society)at our institute, prospectively. Thirty five consecutive patients who had superficial esophageal SCC showing Type B2 microvessel and treated by ESD(endoscopic submucosal dissection)were enrolled in this study from March 2011 to June 2013. Three lesions were histological diagnosed as pT1a-EP/LPM, 23 lesions were defined as tumor depth of pT1a-MM or pT1b-SM1, and the remaining 9 lesions were determined as pT1b-SM2. The accuracy rate of the tumor depth of invasion on the targeted area diagnosed as Type B2 vessels by magnified endoscopy with NBI(narrow band imaging)was 68.6%(24/35). The specificity and the sensitivity of Type B2 vessel was 94.1%and 75.0%, respectively. The reason of misdiagnosis was that it was difficult to determine if the microvessel resemble loop form or not and if the variation of diameter or regional area of Type B2 vessel existed. So an investigation in detail was thought to be needed according to the relation between these findings and the tumor depth of invasion.

 In the near future, a prospective multicenter study of the usefulness of JES Classification of magnified endoscopy for the diagnosis of superficial esophageal SCC will be commenced.


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