Japanese

The Clinicopathologic Feature of the Early Gastric Cancer of Differentiated and Undifferentiated Mixed Type Yutaro Egashira 1 , Hiroshi Akutagawa 1 , Eiji Umegaki 2 , Kazuhide Higuchi 2 , Yoshinobu Hirose 1 1The Department of Pathology, Osaka Medical College, Takatsuki, Japan 2The Second Department of Internal Medicine, Osaka Medical College, Takatsuki, Japan Keyword: 早期胃癌 , 組織混在型 , 未分化型癌 , マクロ所見 , 組織学的検討 pp.1553-1565
Published Date 2013/10/25
DOI https://doi.org/10.11477/mf.1403113963
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 We investigated 1,318 early gastric cancer lesions in this study. Histologically, of the 1,318 lesions, 404(30.7%)were mixed types. The incidence of mixed type gastric cancer tended to increase with its progress. The characteristic histopathologic findings of the mixed type gastric cancer were“located in M region of the stomach”,“located in the anterior wall or posterior wall of the stomach”,“IIc type of macroscopic type”. In the mixed type gastric cancer, both the incidence of ulceration in the tumor, the rate of submucosal invasive carcinoma, and the incidence of accompanying IIb cancer, were higher than those in the differentiated type or undifferentiated type. The rate of lymphnode metastasis in mixed type gastric cancer was higher than that in the differentiated type or undifferentiated type. We classified the mixed type gastric cancer into separated type(13.6%)and non-separated type(86.4%). The characteristic macroscopic findings of the non-separated type of the mixed type gastric cancer were“whitish color”,“obscurity or disappearance of the gastric area”. The non-separated type of the mixed type gastric cancer consisted of tub2 and por in many cases. In the separated type of mixed type gastric cancer, differentiated adenocarcinoma tended to be located in the marginal zone of the lesion, and undifferentiated adenocarcinoma tended to be located in the central zone of the lesion.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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