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Localized Pseudopolyposis of the Colon Yutaka Imai 1 , Yoshinori Sugino 1 , Kenji Kumakura 1 , Tatsuo Teramoto 2 , Susumu Kodaira 2 1Department of Diagnostic Radiology, Keio University School of Medicine 2Department of Surgery, Keio University School of Medicine pp.1381-1387
Published Date 1986/12/25
DOI https://doi.org/10.11477/mf.1403110088
  • Abstract
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 We experienced a case with localized giant pseudopolyposis of the colon simulating a neoplastic change.

 A 58-year-old Japanese woman with a history of constipation for nearly 20 years was admitted to the Keio University Hospital because of bloody mucus in the stool in 1980. Barium enema and colonoscopy revealed tumor-like polypoid lesion in the ascending colon (Figs. 1 and 2). Ileocecal resection was carried out. The resected specimen showed a giant cluster of nodular, villose, and filiform lesion measuring 8 cm in length and 11 cm in diameter (Fig. 3). Histologic examination revealed the localized area of inflammatory pseudopolyposis without neoplastic change. The mucosa and submucosa were densely infiltrated by inflammatory cells containing foreign body giant cells. But there was no sign of extension of these inflammatory change beyond the muscle layer (Fig. 4).

 In 1981, barium enema and colonoscopy demonstrated a recurrence of polyposis in the anal side of the anastomosis (Figs. 5 and 6). The patient was asymptomatic, though. Mucosal biopsies showed inflammatory change. In 1985, after following up for 4 years and 11 months, colonoscopic study showed the features of the localized colitis with only a few polyp formation (Fig. 8).

 We concluded that this localized pseudopolyposis of the ascending colon and cecum may be due to the right-sided ulcerative colitis.


Copyright © 1986, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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