Mucosal Prolapse Syndrome Following Irritable Bowel Syndrome of Seven Years' Duration, Report of a Case of an Effective Treatment by Conservative Therapy Genya Akahoshi 1 , Kouki Yoshida 1 , Toshifumi Nasu 1 , Tomonori Minoda 1 , Tetsushiro Fukumoto 1 1Department of Internal Medicine, Kitakyushu Municipal Medical Center Keyword: 直腸粘膜脱症候群 , MPS , 過敏性腸症候群 , IBS , salazosulfapyridine , SASP pp.1083-1087
Published Date 1992/9/25
DOI https://doi.org/10.11477/mf.1403109985
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 A case of mucosal prolapse syndrome (MPS) of a 17-year-old male is reported. The patient had been followed up for seven years under the diagnosis of irritable bowel syndrome (IBS) without any significant therapy. He complained of tenesmus and had mucohematochezia, and was diagnosed as MPS by barium enema (Fig. 1), colonofiberscopy (Fig. 2) and ultrasonography (Fig. 4) etc. Rectal biopsy revealed fibromuscular obliteration (Fig. 3) confirming the diagnosis of MPS. By instructing the patient to refrain from straining and to void stool less frequently, and also by psychosomatic therapy, mild laxative and salazosulfapyridine (SASP), much improvement was seen after two months (Fig. 5). To our knowledge, this is the first case to prove that MPS (polypoid type) could occur in a natural course after a long history of IBS. It is also interesting that conservative therapy including SASP was effective in this case.

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