Intestinal Amebiasis K. Sakamoto 1 , Y. Shimoda 2 , T. Fuchigami 3 , A. Iwashita 4 1Department of Internal Medicine, Kyushu Central Hospital 2Department of Radiology, Faculty of Medicine, Kyushu University 3The Second Department of Internal Medicine, Faculty of Medicine, Kyushu University 4The Second Department of Pathology, Faculty of Medicine, Kyushu University pp.361-372
Published Date 1983/4/25
DOI https://doi.org/10.11477/mf.1403109357
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 In order to know clinical characteristics of intestinal amebiasis, a total of 32 cases were analyzed. Three of those were our experienced cases and the others were reported cases in Japan during a period of ten years from April 1972 to March 1982.

 Only 11 cases (46%) had a history of travel to foreign countries. One of the radiographic and endoscopic characteristics was multiple tiny ulcers with central yellowish coat surrounded by slight elevation and halo. Detectability of Entamoeba histolytica was 53% (9 out of 17 cases) in feces, 82% (18 out of 22 cases) in biopsy specimens and 100% (3 cases) in colonic mucus. As for the site of lesion, 34 per cent were in the rectum and sigmoid colon, 28% in the entire colon and 16% in the cecum or in the ileocecal region. In one of our experienced cases a lesion was suspected on radiography to exist in the appendix. Several surgical or autopsy cases had severe diseases such as extensive necrosis, huge ulceration and subsequent perforation and peritonitis.

 Metronidazole had therapeutic effects on most of the cases with intestinal amebiasis. Steroid was administered on five of the reported cases, and three of them had fatal prognosis. It seems most important to take intestinal amebiasis into consideration in the differential diagnosis of ulcero-hemorrhagic diseases of the colon. Steroid should not be used until the disease is ruled out.

Copyright © 1983, Igaku-Shoin Ltd. All rights reserved.


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