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Japanese

A Case of Gastric Tuberculosis Showing Peculiar Macroscopic Findings R. Horide 1,2 , T. Kojima 2 , A. Goto 2 , S. Doi 1 , K. Kyo 1 , T. Yoshii 3 1Horide Hospital 2Harima Research Group of Gastroenterology 31st Dept of Pathology, Saitama Medical School pp.1061-1066
Published Date 1976/8/25
DOI https://doi.org/10.11477/mf.1403107391
  • Abstract
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 A 29-year-old woman had complained of general malaise, loss of appetite and pain in the upper abdomen since the summer of 1974. In the beginning of December 1974. she came to us for checkup with chief complaints of nausea and occasional vomiting. X-ray examination revealed poor distensibility of the entire upper part of the corpus, mural rigidity and narrowing of the lesser curvature with a shadow defect on the greater curvature opposite to the angle. Tentative X-ray diagnosis was scirrhous carcinoma. Endoscopy disclosed slight depression of almost the entire gastric mucosa with white coating it. The depression on the greater curvature opposite to the angle was more striking. The floor of the ulcer was markedly uneven. Epithelioid tubercles in the muscularis propria were shown by biopsy. Medical management was of no avail. Gastric symptoms became intense along with melena to such a degree that we had to perform total gastrectomy.

 Macroscopically the resected specimen showed an oval shallow ulcer extending from the antrum up to the cardiac region with the lesser curvature side as its center. Histologically a great number of epithelioid tubercles mixed with Langhans giant cells were seen in the muscularis propria. Some of them showed caseous necrosis. Epithelioid tubercles were also seen in the walls of venules and arterioles of the subserosa.

 Although tuberculosis of the stomach has been reported since relatively old times, mostly it was a necropsied case. During the past 8 years even with increasing advance in gastric examinations, diagnosis of gastric tuberculosis, prior to either surgical operation or autopsy, has been made only in 3 cases.

 The case presented here is a rare instance, diagnosed by biopsy before the operation and characterized by its short course, rapid aggravation of clinical symptoms and extensive lesions.


Copyright © 1976, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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