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Acinar Cell Carcinoma of the Head of Pancreas: A case report of 5 years survival after pancreaticoduodenectomy S. Izumoi 1,2 , K. Takagi 3 1Department of Surgery Cancer Institute Hospital pp.91-98
Published Date 1976/1/25
DOI https://doi.org/10.11477/mf.1403107079
  • Abstract
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 Acinar cell carcinoma of the pancreas has been reported to be 13% of entire carcinoma of the pancreas by Miller (1951), although long-termed survival over 5 years is not yet reported, as far as authors reviewed. This is a case report on curative resection which was performed on one of 2 acinar cell carcinomas diagnosed by histological examination of 66 cases of pancreatic carcinoma.

 Case : Thirty three year-old female without anemia, jaundice or weight loss, was admitted with chief complaint of abdominal mass. It was the size of a goose egg, immobile and located in the right hypochondrium. Duration of illness was 10 months.

 Gastrogram, hypotonic duodenography revealed convexity of the duodenum without Frostberg's phenomenon, irregularity of the duodenal mucosa relating to the extramural compression of tumor, without ulceration. Drop infusion cholecystocholangiogram demonstrated that the choledocus was not dilated but deviated laterally by tumor. Selective angiography revealed a space-occupying lesion showing cystic formationand highly developed vascularity. Coeliac angioscintinography (131 IMAA) suggested pancreas cyst.

 Endoscopic examination of the duodenum documented that the mucosa of entire duodenum was free from lesion but endoscopic cannulation of papilla of Vater was impossible. Cytology of duodenal juice resulted in Class I. Pancreaticoduodenectomy was performed on 5 th Nov., 1969. Operative findings were that the large encapsulated tumor having abundant blood vessels 12×10×10 cm in size was located in the head of pancreas without any evidence of metastasis in the regional lymph nodes. Histological diagnosis was well differentiated acinar cell carcinoma of the pancreas. Atypism of the nuclei was not so prominent Tumor was encountered as a slow growing malignant one from the point of view of huge tumor and of partial invasion to capsule. Postoperative course was uneventful showing no evidence of metastasis or recurrence at the time of 5 years and 2 months after surgery.


Copyright © 1976, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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