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Japanese

Anaplastic Large-cell Lymphoma (So-called Ki-1 Positive Lymphoma) of the Stomach, Report of a Case Takashi Nikaido 1 , Junko Fujisaki 2 , Keizo Takagi 1 , Masahiro Ikegami 1 , Tadakazu Shimoda 1 , Yunosuke Inoue 3 1Department of Pathology, The Jikei University, School of Medicine 2Department of Endoscopy, The Jikei University, School of Medicine 3Inoue Hospital Keyword: Ki-1陽性リンパ腫 , 節外性 , 胃悪性リンパ腫 pp.1075-1082
Published Date 1993/9/25
DOI https://doi.org/10.11477/mf.1403106265
  • Abstract
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 A case of a 77-year-old man with anaplastic large cell lymphoma of the stomach is reported. He was admitted complaining of epigastralgia. No superficial lymph nodes were palpable. Results of laboratory data on admission were unremarkable. Double contrast radiograph of the stomach demonstrated irregular and nodular elevation and irregular niche. Endoscopi cexamination demonstrated multiple white coating which seems to be adhesion, and surrounding elevation reveals a large nodule and has bridging fold. Clinical, radiological, and endoscopic findings were suggestive of non epithelial neoplasms including malignant lymphoma. Total gastrectomy was performed. Histological findings revealed diffuse and/or cohesive growth of the tumor cells with abundant cytoplasm and nuclear pleomorphism. Reed-Sternberg-like multi-nucleated giant cells were occasionally seen. It was difficult to distinguish between anaplastic carcinoma and non-Hodgkin's lymphoma in the histological findings. The tumor cells were immunoreactive with Ber-H2 (Ki-1, CD30) and EMA on cell surface and para-nuclear area. Cytokeratins, LCA, L26 (pan B), and Leu 22 (pan T) showed negative reaction.

 This is an interesting case of extranodal anaplastic large-cell lymphoma. Ki-1 positive lymphomas of the gastro-intestinal tract are reviewed.


Copyright © 1993, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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