Severe Candidiasis in the Oral Cavity and the Esophagus that Led to Diagnosis of Human Immunodeficiency Virus (HIV) Infection, Report of a Case Yoshiya Yamada 1 , Kumiko Momma 1 , Nobuhiro Sakai 1 , Misao Yoshida 2 , Morio Koike 3 1Department of Gastroentertology, Tokyo Metropolitan Komagome General Hospital 2Department of Surgery, Tokyo Metropolitan Komagome General Hospital 3Department of Pathology, Tokyo Metropolitan Komagome General Hospital Keyword: 食道力ンジダ症 , 上部消化管内視鏡検査 pp.1422-1424
Published Date 1994/12/25
DOI https://doi.org/10.11477/mf.1403106023
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 A 30-year-old homosexual male was admitted to our hospital because of odynophagia caused by severe candidiasis in the oral cavity and the esophagus. Further examination revealed HIV infection. Candidiasis showed remarkable improvement after treatment for four days, and it allowed us to detect concomitant ulcers in the middle and lower esophagus which had been covered by thick coatings at the time of the first endoscopy. Studys on bite biopsy specimens from the esophageal ulcers revealed cytomegalovirus (CMV) infection. Odynophagia had disappeared in a few days and endoscopic findings of esophageal ulcers had changed into scars three weeks after application of Foscarnet.

 Recently, the number of cases with sexualy transmitted HIV infection has increased. Some of them were not aware of HIV infection, and came to know about it through evaluation of upper gastrointestinal disorders. In cases with severe candidiasis in the oral cavity or the esophagus, HIV infection should be considered as a possible cause.

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