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Japanese

Pathological Studies of Gastric Carcinoma Resembling Submucosal Tumor Kayoko Kawada 1,2 , Shingo Ishiguro 1 , Naoko Tsuji 1 1Department of Pathology, The Cencer for Adult Disease 2The Third Department of Internal Medicine, Osaka City University Medical School Keyword: 粘膜下腫瘍様胃癌 , 粘膜下腫瘍 , 鑑別診断 , 組織型 pp.739-746
Published Date 1995/5/25
DOI https://doi.org/10.11477/mf.1403105423
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 A Study aimed as comparing pathologic findings in 12 cases of adenocarcinomas resembling submucosal tumors (SMT-like carcinoma; SMTC) with findings in 29 cases of submucosal tumors (SMT) such as leiomyoma, heterotopic pancreas or neurogenic tumors, and to detect pathologic features by which SMTC can be distinguished from those of SMT.

 Statistically, significant differences were found between SMTC and SMT in the ratios of height to width of the tumors, of size of craters to size of tumor, and of depth to width of craters. Histologically, 12 SMTC were divided into five types; 1) poorly solid carcinomas including neuroendocrine carcinomas and carcinomas with lymphoid stroma, 2) carcinomas with massive lymphocytic infiltration irrespective of histologic types, 3) carcinomas with marked fibrosis around the tumors, 4) mucinous carcinomas, 5) carcinomas arising from heterotopic glands, and 6) other types. The elevation of SMTC appeared to be able to be ascribed to the occurrence of fibrous accumulation due to excessive submucosal fibrosis, massive lymphoid infiltration, submucosal heterotopic glands or mucinous adenocarcinoma with mucous lake.

 In comparison with SMT, SMTC tended to arise in the A-area, to have a lower height with an irregular circumferential margin of the elevated part of the tumor, to have larger, shallow craters with irregular margins. The craters of SMTC, when deeply excavated, tended to have concave inner walls.


Copyright © 1995, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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