Churg-Strauss Syndrome with Multiple Ulcers of the Gastrointestinal Tract, Report of a Case Takashi Nishiyama 1 , Ken-ichiro Inoue 1 , Kiyoshi Konoura 1 , Minoru Itsuno 2 , Kazuya Makiyama 2 1Department of Internal Medicine, Inoue Hospital 2he Second Department of Internal Medicine, School of Medicine, Nagasaki University Keyword: Churg-Strauss症候群 , アレルギー性肉芽腫性血管炎 pp.584-588
Published Date 1995/3/25
DOI https://doi.org/10.11477/mf.1403105390
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 A 43-year-old man, who had been diagnosed as having bronchial asthma six months prior to admission, developed a fever, abdominal pain, diarrhea and skin eruptions. The laboratory data showed marked eosinophilia and elevation of the serum IgE. Endoscopic examination showed multiple ulcers in the stomach, duodenum and colon. The biopsy specimens taken from the skin and Gastrointestinal (GI) tract showed angitis accompanied by proliferated endothelial cells and an infiltrate of eosinophils. Based on these clinical and histological findings, this case was diagnosed as ChurgStrauss syndrome. By administration of steroid, the multiple ulcers of GI tract and purpuric eruptions disappeared, and the number of eosinophil and serum concentration of IgE decreased to normal level. It is necessary to perform the biopsy from the affected area quickly in order to make a diagnosis of the angitis, and the administration of steroid is effective for Churg-Strauss syndrome.

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