Clinical Features of Gastric Carcinoids Analysis of 17 Cases Katsuya Hirakawa 1 , Mitsuo Iida 1 , Takayuki Matsmoto 2 1Division of Gustroenterology, Deportment of Medicine, Kawasaki Medical School 2Department of Endoscopic Diugrzostics and Therapeutics, Kyushu University Hospital Keyword: 胃カルチノイド , A型胃炎 , 萎縮性胃炎 , X線診断 , 内視鏡診断 pp.1381-1393
Published Date 2000/10/25
DOI https://doi.org/10.11477/mf.1403104892
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 We classified 17 cases of gastric carcinoids according to the serum gastrin level and the histology of the background mucosa. Thirteen carcinoids were regarded to be Type Ⅰ (hypergastrinemia with atrophy of the background mucosa) while another was classified into Type Ⅱ (hypergastrinemia without atrophy) and the remaining three into Type Ⅲ (normogastrinemia) . While Type Ⅰ carcinoids occurred predominantly at the gastric corpus in multiplicity, there were no differences in the histologic and endoscopic findings of the tumor among the three types of carcinoid. We then compared clinical and histologic findings in five cases of autoimmune gastritis with carcinoid and 14 cases without carcinoid. Overall, there was a significant correlation between histologic grade of atrophy and scores for atrophy determined by radiography and endoscopy. While the grade of atrophy in the background mucosa in both groups was the same, there was a tendency that the former cases to be younger and their serum gastrin levels to be higher than the latter cases. These findings suggest that confirmation of clinical parameters, as well as background mucosa, is mandatory for the diagnosis of carcinoid in autoimmune gastritis, and possibly, for the diagnosis of Type Ⅰ gastric carcinoids.

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