Local Recurrence of Esophageal Squamous Cell Carcinoma after Endoscopic Esophageal Mucosal Resection Tsuneo Oyama 1 , Yoshinori Miyata 1 , Shinji Okaniwa 1 , Yoko Nakamura 1 , Shigeru Yamada 1 1Department of Internal Medicine, Saku Central Hospital Keyword: 食道癌 , 粘膜切除 , EMR , 局所再発 pp.1217-1222
Published Date 1996/9/25
DOI https://doi.org/10.11477/mf.1403104303
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 Endoscopic esophageal mucosal resection (EEMR) is an effective treatment for esophageal superficial cancer. The local recurrence rate of EEMR was 3.1% (two in 65 lesions) . The depth of invasion of the two local recurrent cases was m2. Macroscopically, they were 0-Ⅱc+Ⅱb type and the margin of the iodine unstained area was partially unclear. In one case, a local recurrence was found by chromoendoscopic examination three months after EEMR. In the other case, the two month post-EEMR follow-up examination did not disclose a local recurrence, but seven month examination did. For detecting a local recurrence at an early phase, endoscopic iodine staining should be performed both three and six months after EEMR.

 Both cases were treated by re-EEMR, but a “re-recurrence” was found in the second case, which was treated by laser irradiation. Margin of the iodine unstained lesion became unclear about one month after iodine spreading. So EEMR should be performed one month or later the last endscopic iodine staining.

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