潰瘍性大腸炎における虫垂病変―手術標本からみた虫垂病変

Appendiceal Involvement in Ulcerative Colitis: Histopathological Study Using Operative Specimen

要旨　潰瘍性大腸炎における虫垂病変と大腸病変との関連について検討するために，虫垂について検索しえた手術例41例について組織学的に検討したところ，27例（66％）において虫垂病変が確認され，活動期14例，緩解期13例，正常3例，萎縮虫垂11例であった．虫垂病変と罹患範囲，重症度との間には関連がなかったことから虫垂病変は大腸病変と独立して推移している可能性が示唆された．

　To investigate the relationship between the appendiceal involvement and colitis, histopathological study using 48 operative specimens was performed. Three out of 48 patients had undergone appendectomy before the onset of the disease. The appendectomy rate among our patients was 6％, which was significantly lower than that in the normal population. From investigation using 41 specimens with appendices available, appendiceal involvement was noticed in 27 patients (66％) .

　Their histological stages were active in 14, quiescent in 13, normal in 3, and atrophic in 11 patients. No relationships were found between the appendiceal involvement and the extent of colitis, nor between the appen-diceal involvement and the severity of the disease.

　These results have indicated that appendiceal inflammation is independent of colitis. In all of the cases with active appendiceal involvement, however, presence or previous evidence of inflammation was observed. In conclusion, appendiceal involvement was seemed to change independently of the colitis. Skip lesion of the appendix in ulcerative colitis was identified in 3 cases (7％) in our series.