The Difference between Cap Polyposis and Mucosal Prolapse Syndrome: from the Pathological Standpoint of View Akinori Iwashita 1 1Department of Pathology, Chikushi Hospital, Fukuoka University Keyword: cap polyposis , 粘膜脱症候群 , 直腸孤立性潰瘍症候群 , fibromuscular obliteration pp.651-660
Published Date 2002/4/25
DOI https://doi.org/10.11477/mf.1403103509
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 The concept, morphologic characteristics and pathogenesis of cap polyposis (CP) and mucosal prolapse syndrome (MPS) was briefly described according to the literature. In addition, in order to know the similarities and differences of the two disorders, three cases of CP and 21 cases of MPS were studied comparatively from the histopathological standpoint. The degree of proliferation and dilatation of capillaries was moderate or severe in MPS, whereas, in CP, it was mostly mild. Fibromusculosis in MPS is usually composed of smooth muscle cells and fibrous components and it often extends from the middle to the superficial portion of the mucosa from a thickened muscularis mucosae. In contrast to this, fibromusculosis in CP is composed of thin bundles of smooth muscle fibers, and it is recognized in the deepest portion of the mucosa and seldom extends beyond the middle layer. On the other hand, there was a tendency for the degree of granulation-tissue formation and inflammatory cell infiltration to be higher in cases of CP than in those of MPS. From those results it was concluded that the two disorders are independent clinical entities and should be recognized as such.

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