Gastric Cancer Screening by Serum Pepsinogen Levels - Compared with Radiofluorography Goro Yamaki 1 , Toshiaki Shiga 1 1Department of Gastroenterology, Tokyo Metropolitan Cancer Detection Center Keyword: ペプシノーゲン , 胃癌 , 集団検診 , 間接X線検査 pp.1591-1597
Published Date 2001/12/25
DOI https://doi.org/10.11477/mf.1403103381
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 A notice for primary screening by photofluorography of the stomach is sent out to all residents. Every year, approximately 6 million people go through the screening. Another recent trend for primary screening is to measure the serum pepsinogen level.

 Among people over 50 years of age, the positive rate for standard was 40%, that for moderate positive was 27% and that for severe positive was 11%. The figures for early cancers, in 37 standard cases out of 51 early cancers (72.5%) were included. For moderate positive 31 out of 51 cases of early cancers (60.8%) were included. For severe positive 19 out of 51 cases of early cancers (37.3%) were included. We were also able to seach the same conclusion for advanced cancers. There is no relation between PG (+) and PG (-) cases in terms of size, location and depth of invasion, but the undifferentiated type is more common in PG (-) cases. The screening method by photofluorography has been encouraged for many years. The X-ray depiction rate of early and advanced cancers used in this study was 46.3% of the early cancers and 92.7% of the advanced cancers. The largest problem remaining in this method is the quality of endoscopic examination.

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