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Japanese

Protruding Undifferentiated Adenocarcinoma Invading as far as the Submucosal Layer in the Esophagogastric Junction, Report of a Case Osamu Hosokawa 1 1The Department of Surgery, Fukui Prefectural Hospital Keyword: 食道胃接合部早期癌 , 充実型低分化腺癌 , 腸型粘液形質 , specialized columnar epithelium , Barrett上皮 pp.703-707
Published Date 2001/4/25
DOI https://doi.org/10.11477/mf.1403103218
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 A 71-year-old man was diagnosed as having a prot-ruding lesion in the esophagogastric junction. X-ray examination showed the lesion with a clear margin and a barium plaque on the surface. Endoscopic examination showed the red lesion was surrounded with esophageal mucosa stained by iodine at the oral side and in contact with the gastric mucosa at the anal side. Since the biopsy specimen obtained from the lesion was positive for adenocarcinoma, the lower esophagus and proximal stomach was resected. Macroscopically the red protruding lesion measured 1.6 cm in diameter. Microscopically, poorly differentiated adenocarcinoma cells solidly invaded the submucosal layer. Immunohistochemical study showed the cancer cell as the intestinal phenotype. The lesion was adjacent to intestinal metaplasia called specialized columnar epithelium. Therefore, we suspect that the lesion had arisen from the short segment with intestinal metaplasia at the esophagogastric junction.


Copyright © 2001, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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