Duodenal Carcinoid Tumor: Strategy of Treatment Yoshihide Asaumi 1 , Yasuharu Kaizaki 2 , Osamu Hosokawa 3 , Tamon Miyanaga 1 , Naoyuki Ibe 4 , Kenji Doden 1 , Masakazu Hattori 1 , Yasuo Hashizume 1 1Department of Surgery, Fukui Prefectural Hospital, Fukui, Japan 2Department of Pathology, Fukui Prefectural Hospital, Fukui, Japan 3Department of Surgery, Yokohama Sakae Kyosai Hospital, Yokohama, Japan 4Department of Digestive Medicine, Fukui Prefectural Hospital, Fukui, Japan Keyword: 十二指腸 , カルチノイド , 神経内分泌腫瘍 , MIB1 index , 治療方針 pp.1626-1633
Published Date 2011/10/25
DOI https://doi.org/10.11477/mf.1403102381
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 Duodenal carcinoid tumors are relatively rare. It is difficult to determine a strategy for their treatment. We report a clinicopathologic study of 21 duodenal carcinoid tumors in our hospital. Seventeen cases were observed in the bulbus. Eighteen cases were not more than 10mm in size. For treatment, nine cases were subjected to surgery with lymph node dissection. Nine cases underwent EMR(endoscopic mucosal resection)and three cases have been under follow-up without any treatment. Metastasis to the liver and lymph node was recognized only in one case. Two cases died due to other carcinomas but the others are still living. MIB1 index of the proliferative activity was not correlative with tumor size and depth of invasion. A strategy for treatment for duodenal carcinoid tumor based on the pathological characteristics of EMR specimen and metastasis, was recommended.

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