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The Characteristic of Adenoma and Carcinoma Arising from Brunner's Gland Makoto Takahashi 1 , Syuji Hamada 2 , Kazuhiko Nakamura 3 , Eikichi Ihara 3 , Moritomo Iju 1 , Kenichi Suda 4 , Daisuke Korenaga 5 , Kenji Takenaka 5 , Mikako Osada 6 , Minako Hirahashi 6 , Takashi Yao 7 1Department of Internal Medicine, Fukuoka City Hospital, Fukuoka, Japan 2Hamada Internal Medicine Clinic, Fukuoka, Japan 3Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 4Department of Thoracic Surgery, Aichi Cancer Center Hospital, Nagoya, Japan 5Department of Surgery, Fukuoka City Hospital, Fukuoka, Japan 6Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 7Department of Human Pathology, Juntendo University School of Medicine, Tokyo Keyword: 十二指腸 , Brunner腺 , 腺腫 , 十二指腸癌 pp.1619-1625
Published Date 2011/10/25
DOI https://doi.org/10.11477/mf.1403102380
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 Duodenal adenoma and carcinoma arising from Brunner's glands were extremely rare. Brunner's adenoma is mostly recognized as a sessile or subpedunculated submucosal tumor, and some of them present central depression. Endoscopic ultasonography revealed homogeneous an isoechoic or hypoechoic tumor in the third layer. Histologically, it is assumed to be of Brunner gland origin but to show clearly atypical tissue in comparison with a normal Brunner gland.

 Duodenal carcinoma originating from Brunner's gland, compared with other duodenal cancers, often reveals a submucosal tumor-like elevated lesion with a central depression. Endoscopic ultasonography revealed an isoechoic or hyperechoic mass in the third layer, in which the hypoechoic area is observed as cystic space.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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