Mucinous Carcinoma of the Rectosigmoid Colon, Transforming from a Pedunculated(Ip type)Polypoid Cancer in about One Year, Report of a Case Ryota Higuchi 1 , Fumihiko Nakamura 1 , Yoshinori Matsuura 1 , Katsuya Hattori 1 , Hiroaki Suda 1 , Hironori Kowazaki 1 , Akihiko Ohta 2 , Masahiko Kuroda 3 , Jyun Matsubayashi 4 1Department of Gastroenterology, Kosei Chuo General Hospital, Tokyo 2Ota Clinic, Tokyo 3Department of Pathology, Tokyo Medical University, Tokyo 4Department of Diagnostic Pathology, Tokyo Medical University, Tokyo Keyword: 有茎性ポリープ , 大腸粘液癌 , 肉眼形態変化 , 発育進展 , 大腸印環細胞癌 pp.1777-1784
Published Date 2009/10/25
DOI https://doi.org/10.11477/mf.1403101789
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 A 40-year-old male was referred to our hospital because of abdominal pain. Barium enema revealed a pedunculated polypoid lesion with a shallow depressive area on the surface of the head and tensed thick stalk, approximately 17mm in size, in the rectosigmoid colon, which was presumed to be an early colonic cancer invading to the submucosal layer. However, the patient did not revisit for further treatment. About one year later, he was admitted due to watery diarrhea. At this time barium enema showed an elevated lesion like a submucosal tumor in the same area. The top of the lesion was depressed and the center was protruded. It looked like a pumpkin in appearance(2-type cancer). The biopsied specimen revealed signet-ring cell carcinoma. High anterior resection was performed. The resected specimen revealed the signet-ring cell carcinoma with poorly differentiated adenocarcinoma mainly in the mucosal layer and mucinous carcinoma from the submucosal layer to the serosa. Finally we diagnosed mucinous carcinoma of the colon.

 Mucinous carcinoma, transforming from a pedunculated polyp, has never yet been reported.

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