Present State of Endoscopic Detection of Minute and Small Esophageal Squamous Cell Carcinoma:Conventional Observation and Iodine Staining Hideo Shimada 1 , Hiroyasu Makuuchi 1 , Souji Ozawa 1 , Osamu Chino 1 , Takayuki Nishi 1 , Yoshifumi Kise 1 , Tomoko Hanashi 1 , Tadashi Hara 1 , Soichiro Yamamoto 1 , Minoru Nakui 1 , Akito Kazuno 1 , Chie Inomoto 2 1Department of Surgery, Tokai University, School of Medicine, Isehara, Japan 2Department of Pathology, Tokai University, School of Medicine, Isehara, Japan Keyword: 微小食道癌 , 小食道癌 , 小ヨード不染 , 内視鏡的切除 pp.1655-1667
Published Date 2009/10/25
DOI https://doi.org/10.11477/mf.1403101774
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 At present there is no international definition of small esophageal cancer. We defined small esophageal cancer as that less than 10mm and minute esophageal cancer as that less than 5mm in size.

 Until now, 796 cases of superficial esophageal cancer have been treated in our institution by Endoscopic resection. Among them 68cases were small esophageal cancers and 8 cases were minute esophageal cancers.

 We analyzed small and minute esophageal cancer, concerning its clinical date, diagnosis, clinicopathological findings according to the Japanese Guide lines for Clinical and Pathologic Studies of the esophagus.

 Concerning the depth of invasion, all cases of 0-IIb were limited to the lamia propria mucosa(T1a-LPM), while tumors containing elevated or protruding components seemed more invasive.

 As for endoscopic diagnosis, 28 cases of minute and small esophageal cancer were detected by conventional observation. However, 48cases(63.2%)needed iodine staining for their lesions to be detected by endoscopic examination.

 Concerning the gross findings, type 0-IIb(28cases:36.8%)and 0-IIc(33cases:43.4%)lesions occupied 80.2% of all these lesions.

 Concerning the depth of invasion, all cases of type 0-IIa or 0-IIb were limited within a lamina propria of the mucosa(T1a-LPM).

 However tendency was recognized for 0-IIc type tumors containing marginal elevation or 0-I of protruding component to be more invasive deeper than T1a-MM type tumors.

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