Pathologic Differential Diagnosis of Tumors of the Small Intestine Yoichi Ajioka 1 , Gen Watanabe 1 , Takashi Kato 1 1Division of Molecular and Diagnostic Pathology, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan Keyword: 小腸腫瘍 , 肉眼的鑑別 , 組織学的鑑別 , 免疫染色 pp.499-512
Published Date 2008/4/24
DOI https://doi.org/10.11477/mf.1403101322
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 Various types of tumors have to be taken into consideration for differential diagnosis of tumors of the small intestine. For elevated tumors, epithelial neoplasms, malignant lymphoma, lipoma, hemangioma, and GIST can be differentiated by whether or not it is submucosal tumor, surface appearance and color, and the presence of small but deep associated ulcer. For ulcerted tumor, number of lesions (single or multiple), stricture of the intestinal wall, shape of the ulcer margin are important findigs for the diagnosis, and metastatic tumor, malignant lymphoma, and advanced tubular adenocarcinoma can be differentiated. Howere, it seems to be difficult to differentiate advanced poorly differentiated adenocarcinoma with medullary growth and diffuse large B cell lymphoma. For the confirmation of the diagnosis, immunohistochemistry is necessary and it is recommended to use keratin, vimentin, S-100, LCA, KIT, CK20, and CK7 as a basic set.

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