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Epidermization of the Esophagus, Report of Two Cases Yasumasa Ezoe 1 , Manabu Muto 2 , Satoshi Fujii 3 1Department of Multidisciplinary Cancer Treatment, Graduate School of Medicine, Kyoto University, Kyoto, Japan 2Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan 3Pathology Division, Research Center for Innovative Oncology, National Cancer Center, Kashiwa, Japan Keyword: epidermization , epidermoid metaplasia , 類表皮化生 pp.296-300
Published Date 2008/3/25
DOI https://doi.org/10.11477/mf.1403101291
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 We described the clinical features of epidermization, focusing on endoscopic and histopathological findings. Since the pathological feature of this lesion is a keratinized layer at the surface of the epithelium resembling the epidermis, this lesion has been known as"epidermization". Endoscopically, epidermization seems to be adherent to the esophageal mucosa and to resemble plaques. It has a translucent white color, scaly or shaggy surface without erosion or ulceration, and retains an unstained appearance after staining with Lugol's iodine solution. Differential diagnosis needs to be made based on lesions with similar appearance, such as papilloma, hyperkeratosis, glycogenic acanthosis, localized esophagitis, esophageal candidiasis, and superficial esophageal cancer. To our knowledge, since there are few previous reports of epidermoid metaplasia, both the etiology and the frequency of epidermization are unknown at this time.


Copyright © 2008, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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