The Organic Gastrointestinal Lesions or Functional Bowel Disorders Observed in Systemic Diseases (including Intestinal Lesions that are Provoked by Hepatic, Biliary or Pancreatic Disease) Ken Toshina 1 , Ichiro Hirata 1 1The Second Department of Osaka medical college Keyword: 系統的疾患 , 全身性疾患 , 器質的消化管病変 , 機能的消化管障害 , 肝胆膵疾患 pp.427-447
Published Date 2003/4/24
DOI https://doi.org/10.11477/mf.1403100897
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 When we observe the gastrointestinal (GI) tract using endoscopy, it is always necessary to consider and understand that potential systemic diseases may be indicated by what we see. The GI abnormalities mentioned in this manuscript are divided into organic GI lesions and functional bowel disorders. Concerning the diseases that were introduced in particular, minute description of each of them, was made, but those that were not introduced in particular were merely mentioned.

 Firstly, we described the following organic GI lesions ; a) Zollinger-Ellison syndrome (refractory and easy-relapsing peptic ulcers, much retention of gastric juice and (or) giant folds in the stomach are observed). b) Groove pancreatitis (elevated or stenotic lesion like a submucosal tumor, which has relatively smooth, or sometimes irregular margin, often exists on the medial wall of the descending portion of the duodenum). c) Pancreatic cancer (stenosis is caused by direct invasion into the stomach or duodenum). d) Systemic malignant lymphoma (multiple elevated lesions etc. are observed in the GI tract). e) Adult T-cell leukemia/lymphoma (ATLL) (organs are easily invaded, the invasion is also observed in the GI tract, and provokes various digestive symptoms). f) Acquired immunodeficiency syndrome (AIDS) (various GI lesions arise from opportunistic infections). g) Intestinal endometriosis (one sided elevation and (or) granularity of the mucosa mainly on the anterior wall of Rs~distal sigmoid colon are characteristic).

 Secondly, functional bowel disorders (digestive and absorptive disorder,GI movement disorder). Their symptoms, original diseases and diagnosis were mentioned as malabsorption syndrome and protein-losing gastroenteropathy. In digestive and absorptive disorder and irritable bowel syndrome (IBS), we described systemic diseases or others which need to be ruled out when diagnosis is made.

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