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Treatment for Gastric MALT Lymphoma Unresponsive to H. pylori Eradication Tsutomu Chiba 1 1Department of Gastroenterology and Hepatology, Kyoto University Keyword: MALTリンパ腫 , H.pylori , API2-MALT1 , 放射線療法 , 手術 pp.309-315
Published Date 2004/3/25
DOI https://doi.org/10.11477/mf.1403100442
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 When gastric MALT lymphoma is unresponsive to eradication treatment for H. pylori, the presence or absence of API2-MALT1 fusion transcript should be examined. If the fusion transcript is present, then careful observation may be one of the treatment options, but generally monotherapy with surgical operation, radiation or chemotherapy can be considered. On the other hand, in cases without the fusion transcript, following short term careful observation, monotherapy with surgical operation, radiation, chemotherapy, or sometimes combination therapy should be promptly performed. Moreover, it should be noted that there are some cases, in which MALT lymphoma aggravates very rapidly immediately after eradication. Intensive observation is required for such cases.

 1) Department of Gastroenterology and Hepatology, Kyoto University, Kyoto, Japan


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