Laterally Spreading Tumor of Colon―Definition and History Shin-ei Kudo 1 1Digestive Disease Center, Showa University Northern Yokohama Hospital Keyword: laterally spreading tumor , LST , 側方発育型 pp.1721-1725
Published Date 2005/12/25
DOI https://doi.org/10.11477/mf.1403100176
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 Among colorectal neoplasms, there is a certain group that are likely to extend laterally, rather than vertically along the colonic wall. In the last 20 years, many cases of these tumors have been reported, and these tumors are defined as LST : laterally spreading tumor. The difinition includes only tumors more than 10mm in diameter. LST are classified into granular type and non-granular type. The tumors which have been recognized as nodule aggregating lesions are classified as granular type. The granular type are further divided into two groups ; homogeneous type and mixed nodular type. Non-granular types are divided into two more group ; flat elevated type and pseudo-depressed type. Since the term nodule aggregating lesion has been introduced, several terms which stand for these tumors have been used for expression of colorectal tumors extending laterally. Among these terms LST is the best expression for such colorectal tumors. Recently, histopathological study and mutation analysis has made the nature of LST clear. To select appropriate therapy for LST it is important to rely on such analysis.

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