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Japanese

Vitrectomy for proliferative diabetic retinopathy in young adults: Clinical features and surgical outcomes Fumika Kishishita 1 , Ayumi Usui-Ouchi 1 , Risa Nishiguchi 2 , Yoshihito Sakanishi 1 , Keitaro Mashimo 1 , Kazunori Tamaki 1 , Toshiro Sakuma 1 , Rei Ito 1 , Nobuyuki Ebihara 1 1Department of Ophthalmology, Juntendo University Urayasu Hospital 2Department of Ophthalmology, St. Luke's International Hospital pp.109-115
Published Date 2025/1/15
DOI https://doi.org/10.11477/mf.037055790790010109
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Abstract Purpose:To investigate the postoperative visual acuity and complications related to 25 gauge and 27 gauge micro-incision vitrectomy surgery(MIVS)in patients aged below 40 years old with proliferative diabetic retinopathy(PDR), and to identify factors that affect visual prognosis.

Subjects and methods:This study included 35 cases(50 eyes)of PDR patients under 40 years old who underwent initial vitrectomy at Juntendo University Urayasu Hospital from May 2015 to June 2021. Their mean age was 35.1±3.9 years, with a mean follow-up period of 30.5±19.5 months. There were 21 males(28 eyes)and 14 females(22 eyes). Postoperative visual acuity and complications were retrospectively analyzed.

Results:The final postoperative visual acuity was 0.42±0.35 logMAR. The proportion of cases with visual acuity less than 0.1 was 10%, those with 0.5 or better was 68%, and those with 0.7 or better was 58%. Compared to preoperative visual acuity, 68% of cases showed an improvement of 0.2 logMAR after surgery but 14% showed deterioration. Postoperative complications included vitreous hemorrhage in 36% of cases, reproliferation in 14%, and neovascular glaucoma(NVG)in 6%. Postoperative reproliferation significantly affected visual deterioration.

Conclusion:Vitrectomy for young PDR patients improved postoperative visual acuity and reduced incidence of NVG. However, reproliferation remained a significant adverse prognostic factor.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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