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- 参考文献 Reference
・大腿部に生じたclear cell hidradenoma(CCH)を報告した.
・超音波画像検査では低エコー領域に高エコー領域が突出する所見がみられた.
・病理組織学的所見で断頭分泌がみられたものの,免疫化学染色ではluminal cell がcarcinoembryonic antigen(CEA)とepithelial membrane antigen(EMA),34βE12が陽性,clear cellがEMAと34βE12が陽性であったことから,表皮内汗管と真皮内汗管の外壁細胞への分化傾向が考えられた.
(「症例のポイント」より)
A case of clear cell hidradenoma
Oya, Kazumasa1)Taguchi, Shijima2) 1)Department of Dermatology, Faculty of Medicine, University of Tsukuba 2)Dermatology, Mito Kyodo General Hospital
A 32-year-old male presented with a nodule on his left thigh. Physical examination revealed a 15×13-mm dark, dome-shaped nodule. Histopathological examination revealed that the mass consisted of solid and cystic areas. Clear cells and epidermoid cells were seen in the solid area. Duct-like structures lined by a layer of luminal cells were also present. Based on these findings, a diagnosis of clear cell hidradenoma was made. Immunohistochemical studies showed that the luminal cells were positive for carcinoembryonic antigen (CEA), epithelial membrane antigen (EMA) and 34βE12; and the clear cells were positive for EMA and 34βE12, which suggested the tumor had characteristics of acrosyringium with an outer layer consisting of dermal duct cells.

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