皮質-皮質間誘発電位（CCEP）

Intraoperative Cortico-Cortical Evoked Potential

Point

・皮質-皮質間誘発電位（CCEP）は1〜2分で施行可能であり，高い再現性と信頼性から術中にも施行可能である．

・術中CCEPは言語や運動などの機能同定だけでなく，てんかんの病的ネットワークの同定にも有用である．

・Warning signの設定や全身麻酔下でのモニタリング法としての確立が今後求められる．

　In the surgery management of lesions in areas of the eloquent cortices the preservation of brain functions is required. Intraoperative electrophysiological methods are necessary to preserve the integrity of the functional network, such as motor or language areas. Cortico-cortical evoked potentials（CCEPs）have recently developed as a new intraoperative monitoring method because of advantages of a recording time of approximately 1-2 min, no requirement of patient cooperation, and high reproducibility and reliability of the data. The recent intraoperative CCEP studies have shown that CCEP can map the eloquent areas and white matter pathway, such as the dorsal language pathway, frontal aslant tract, supplementary motor area, and optic radiation. To establish intraoperative electrophysiological monitoring even under general anesthesia, further studies are required.