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Improvement of Cerebral Hemodynamic and Metabolic Parameters in a Patient who Presented Intracranial Hypertension Due to Superior Sinus Thrombosis after Lumbo-peritoneal Shunt : Case Report Masaaki HOKARI 1 , Satoshi KURODA 1 , Tatsuya ISHIKAWA 1 , Yoshinobu IWASAKI 1 1Department of Neurosurgery,Hokkaido University Graduate School of Medicine Keyword: single-photon emission computed tomography (SPECT) , positron emission tomography (PET) , sinus thrombosis , intracranial hypertension pp.281-286
Published Date 2005/3/1
DOI https://doi.org/10.11477/mf.1436100049

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  • Abstract
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Cerebral hemodynamic and metabolic changes in intracranial hypertension associated with sinus thrombosis have not been well documented. We report pre- and post-treatment changes in cerebral hemodynamic and metabolic parameters in a 50-year-old male who presented intracranial hypertension due to sinus thrombosis, using single-photon emission computed tomography (SPECT) and positron emission tomography (PET).

 He complained of headache, nausea and double vision and was admitted to our hospital. Neurological examinations on admission revealed papilledema on both sides. Cerebrospinal fluid pressure was 28 mmHg. Cerebral angiography showed occlusion of the superior sagittal sinus and retrograde filling of the ascending cortical veins in the bilateral frontal lobes. 123I-IMP SPECT and 15O-gas PET showed a reduction of cerebral blood flow and oxygen metabolism and an extreme elevation of cerebral blood volume in the bilateral cerebral hemispheres. His complaints resolved after lumbo-peritoneal shunt. Postoperative SPECT/PET studies demonstrated improvement of hemodynamic and metabolic parameters. Intracranial hypertension and associated venous congestion were most likely related to hemodynamic and metabolic abnormalities.


Copyright © 2005, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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