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Sequential Change of SPECT Using 201T1 Chloride During the Treatment of Intracranial Gliomas Hiroshi Seo 1 , Kiyoshi Sato 1 , Toshiya Fujita 1 , Kiyotada Yamada 1 , Osamu Nakai 1 , Akio Komatani 2 1Department of Surgical Neurology, Yamagata University, School of Medicine 2Department of Radiology, Yamagata University, School of Medicine Keyword: 201T1 chloride , treatment , glioma , SPECT pp.537-543
Published Date 1993/6/1
DOI https://doi.org/10.11477/mf.1406900494

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  • Abstract
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The authors followed up the change in SPECT using 201T1 chloride (T1-SPECT) according to the course of treatment of intracranial gliomas and analyzed the difference in T1-SPECT between the stable and progressive groups. The subjects were 26 series of supratentorial giomas subjected to T1-SPECT before and after the treatment (radio-the-rapy and chemotherapy). They were put on T1-SPECT after 10 minutes (early image) and 4 hours (delayed) following 74 MBq of 201T1 chloride intra-venous injection.

Besides, RI count ratio (L/N) in the tumor lesion(L) and contralateral parenhyma (N) was mea-sured. The patients were divided into stable and progressive groups judging from the therapeutic effects, the change in L/N ratio between before and after the treatment was analyzed. The stable group showed a significant post-treatment decrease in L/N ratio compared with a significant post-treatment increase therein for the progressive group. This result suggested T1-SPECT to change according to the course of treatment and to be applicable to the judgement of the therapeutic effect on gliomas.


Copyright © 1993, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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